Extended parasite screening with additional SIBO & intestinal permeability assessment

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Clinical overview

THE PARASITE BOX – XL includes all analyses performed in THE PARASITE BOX – LARGE, and extends the diagnostic scope with functional gut testing for SIBO and intestinal permeability (Leaky Gut).

In addition to identifying parasitic, viral and bacterial pathogens, the XL box provides insight into small intestinal bacterial overgrowth and gut barrier integrity, which may contribute to chronic or recurrent gastrointestinal symptoms.

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Analytical methods

• Microscopy for helminths and unicellular parasites
• Real-time PCR for protozoa, viruses and pathogenic bacteria
• Urine-based biomarkers for SIBO and intestinal permeability (XL exclusive)

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Sample material & turnaround time

• Sample material: Stool sample + urine sample
• PCR results: Typically available within 24–48 hours
• Microscopy results: 5–14 business days

All testing is performed at an EU-based accredited laboratory.

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Parasitological analysis – Microscopy

(Identical to THE PARASITE BOX – LARGE)

Roundworms (Nematodes)

• Ancylostoma duodenale
• Ascaris lumbricoides
• Enterobius vermicularis
• Strongyloides stercoralis
• Trichuris trichiura

Tapeworms (Cestodes)

• Dipylidium caninum
• Diphyllobothrium latum
• Hymenolepis nana
• Taenia saginata
• Taenia solium

Flukes (Trematodes)

• Fasciolopsis buski
• Fasciola hepatica
• Opisthorchis viverrini
• Schistosoma haematobium

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Unicellular parasites, viruses & bacteria

(Identical analytical coverage to THE PARASITE BOX – LARGE)
Includes microscopy and PCR detection of protozoa, broad-spectrum viral PCR and pathogenic bacterial PCR panels as listed above.

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Gut health & functional testing – XL exclusive

In addition to standard stool-based gut health markers, THE PARASITE BOX – XL includes:

SIBO assessment

• Two highly specific urinary biomarkers associated with bacterial overgrowth in the small intestine

Intestinal permeability (Leaky Gut)

• A validated urinary marker reflecting gut barrier integrity

This functional testing adds clinically relevant information in patients with symptoms such as bloating, chronic diarrhoea, malabsorption or treatment-resistant gastrointestinal complaints.

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Medical support & add-ons

As with the Large box, a free digital consultation is included in the event of a confirmed tapeworm infection. Additional PCR and antibody-based tests can be added where clinically appropriate.

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Clinical indication

THE PARASITE BOX – XL is recommended for patients requiring both extensive pathogen screening and functional gut assessment, particularly in complex or long-standing cases.